The countries are Cameroon, Senegal, Algeria, Mali and Tunisia.
The Confederation of African Football (CAF) disclosed this in a post via its Twitter handle on Wednesday.
Tunisia booked a place at the 2022 Africa Cup of Nations after playing a 1-1 draw with Tanzania on Tuesday, while Mali defeated Namibia 2-1 on Tuesday.
Algeria secured their ticket after playing a 2-2 draw with Zimbabwe on Monday, while Senegal won Guinea-Bissau 1-0 on Sunday.
Cameroon have an automatic spot as hosts.
“Cameroon, Senegal, Algeria, Mali, Tunisia.
“19 spots still up for grabs in the last two matchdays,” CAF tweeted.